Detalhe da pesquisa
1.
NRX-0492 degrades wild-type and C481 mutant BTK and demonstrates in vivo activity in CLL patient-derived xenografts.
Blood
; 141(13): 1584-1596, 2023 03 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-36375120
2.
Broad-spectrum cyclic boronate ß-lactamase inhibitors featuring an intramolecular prodrug for oral bioavailability.
Bioorg Med Chem
; 62: 116722, 2022 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35358864
3.
In vitro reassembly of the ribose ATP-binding cassette transporter reveals a distinct set of transport complexes.
J Biol Chem
; 290(9): 5555-65, 2015 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-25533465
4.
High-resolution Crystal Structure of Dimeric VP40 From Sudan ebolavirus.
J Infect Dis
; 212 Suppl 2: S167-71, 2015 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25957961
5.
Crystal structures of Mycobacterial MeaB and MMAA-like GTPases.
J Struct Funct Genomics
; 16(2): 91-9, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25832174
6.
Structural and functional characterization of FabG4 from Mycolicibacterium smegmatis.
Acta Crystallogr F Struct Biol Commun
; 80(Pt 4): 82-91, 2024 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38656226
7.
Discovery and Preclinical Pharmacology of NX-2127, an Orally Bioavailable Degrader of Bruton's Tyrosine Kinase with Immunomodulatory Activity for the Treatment of Patients with B Cell Malignancies.
J Med Chem
; 67(4): 2321-2336, 2024 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38300987
8.
Structural and biophysical comparisons of the pomalidomide- and CC-220-induced interactions of SALL4 with cereblon.
Sci Rep
; 13(1): 22088, 2023 12 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38086859
9.
Discovery and characterization of a selective IKZF2 glue degrader for cancer immunotherapy.
Cell Chem Biol
; 30(3): 235-247.e12, 2023 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36863346
10.
Lipocalin 2 promotes breast cancer progression.
Proc Natl Acad Sci U S A
; 106(10): 3913-8, 2009 Mar 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-19237579
11.
Structural characterization of a ribose-5-phosphate isomerase B from the pathogenic fungus Coccidioides immitis.
BMC Struct Biol
; 11: 39, 2011 Oct 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-21995815
12.
Lipocalin 2 is required for pulmonary host defense against Klebsiella infection.
J Immunol
; 182(8): 4947-56, 2009 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19342674
13.
Structure of the cystathionine γ-synthase MetB from Mycobacterium ulcerans.
Acta Crystallogr Sect F Struct Biol Cryst Commun
; 67(Pt 9): 1154-8, 2011 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21904066
14.
Siderocalins: siderophore-binding proteins of the innate immune system.
Biometals
; 22(4): 557-64, 2009 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-19184458
15.
Parsing the functional specificity of Siderocalin/Lipocalin 2/NGAL for siderophores and related small-molecule ligands.
J Struct Biol X
; 2: 100008, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-32647813
16.
The siderocalin/enterobactin interaction: a link between mammalian immunity and bacterial iron transport.
J Am Chem Soc
; 130(34): 11524-34, 2008 Aug 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-18680288
17.
Backbone chemical shift assignments and secondary structure analysis of the U1 protein from the Bas-Congo virus.
Biomol NMR Assign
; 11(1): 51-56, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-27981424
18.
Ligand co-crystallization of aminoacyl-tRNA synthetases from infectious disease organisms.
Sci Rep
; 7(1): 223, 2017 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-28303005
19.
Structures of aspartate aminotransferases from Trypanosoma brucei, Leishmania major and Giardia lamblia.
Acta Crystallogr F Struct Biol Commun
; 71(Pt 5): 566-71, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25945710
20.
Structure of an ADP-ribosylation factor, ARF1, from Entamoeba histolytica bound to Mg(2+)-GDP.
Acta Crystallogr F Struct Biol Commun
; 71(Pt 5): 594-9, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25945714